Systems engineering is suitably applied to space programming due to the multidisciplinary and complex nature of space missions where systematic design methods are commonly utilized. For designing a spacecraft, knowledge and expertise from different disciplines are required and numerous projects and subprojects need to work simultaneously and in close coordination. The purpose of this article is to analyze the system design process for a CubeSat using a design structure matrix. Considering the characteristics of the design structure matrix method is a powerful design tool that assists in managing the complexity of system design with many parameters. The design structure matrix method offers advantages to address these deficiencies in the design process of a satellite because it considers multiple factors that exist in the design process. The design structure matrix method helps reduce repetitions in the process. This method has been used to show the interdependent relationships between the different components of CubeSat and present the design process at the system level. In this study, 4 main components and their effect on each other have been demonstrated. The process was identified in the form of a matrix. This study aimed to capture the issues, activities, challenges, and opportunities for improving the conception, design, manufacture, testing, launch and operation of small satellite missions and identify lessons learned for process improvements of future missions.